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The review also documented GSHs role in regenerating vitamin E following detoxification of lipid peroxyl radicals, its involvement in the glyoxalase systems detoxification of dicarbonyl stress induced by methylglyoxal and glyoxal, and its regulation of redox signalling through reversible S-glutathionylation of critical protein cysteine residues

[1] NNMT as a Metabolic Research Target Independent research groups have studied NNMT inhibition in diet-induced obese (DIO) mouse models

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