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PI3K/AKT and mitogen activated protein kinase (MAPK) are essential molecules regulate brain insulin signaling (Zheng and Wang 2021)
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Analytical confirmation relies on HPLC at minimum, with mass spectrometry applied where peptide identity needs orthogonal confirmation
However, they also have limitations: many are unstable in the gut, so they are often given by injection, and some have limited human data outside of specific indications
Erythrocyte metabolism
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