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The STEP (Semaglutide Treatment Effect in People with obesity) trials showed that participants lost approximately 1520% of their body weight over 68 weeks, with body composition analyses indicating that roughly 2040% of the total weight lost was lean mass

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If youre taking an oral contraceptive, it is recommended that you use another method of contraception (such as a condom), or switch to a non-oral contraceptive for 4 weeks after starting treatment

High-grade tumors show scant cytoplasmic vacuolation with more prominent nucleoli, atypical mitoses and abundant necrosis (Figures 6, 7 and 8)