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In terms of their structural composition, these agents can be divided into two main categories: modified versions of native GLP-1 that are resistant to DPP-4 and those that mimic Ex-4, activating GLP-1 R in a manner that is comparable to that of native GLP-1

This careful titration process leads to the optimal semaglutide maintenance dose

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GLP-1 agonists commonly cause gastrointestinal side effects: Nausea Vomiting Decreased appetite Diarrhea (occasionally) These side effects can lead to dehydration

Obesity Facts, 13, 6, 572-583