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In clinical studies, NTLA-2002 was well tolerated and led to durable reductions in HAE attacks, supporting the notion that editing KLKB1 can lead to a positive effect on disease
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Studied in: IGF-1 receptor (IGF-1R) binding research, IGFBP interaction studies, protein folding and disulfide structure analysis, and comparative work against native IGF-1 in controlled laboratory models
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The serum is paraben-free, steroid-free, and hypoallergenic
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