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Real-world outcomes: According to a 72-week phase 3b trial, adults with obesity (but without diabetes) treated with tirzepatide were significantly more likely to lose at least 10% or 15% of their body weight than those treated with semaglutide

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ARC, arcuate nucleus

Upon reaction with ROS or electrophiles, GSH becomes oxidized to GSSG, which can be reduced to GSH by the GSSG reductase (GR)

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