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GIP treatment has been shown to reduce glucolipotoxicity-induced cell death in C57 BL/6 and Bax -/- pancreatic islets, but not GIPR -/- pancreatic islets of the mouse models (114)
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Since then, he has continued to see cases and has been contacted by people with NAION from around the world
To provide a concise overview of these heterogeneous findings, representative studies reporting divergent, atypical, or endpoint-dependent responses to GLP-1RA treatment are summarised in Table 2
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