The number of injections required depends on your: Current skin tone Desired skin tone Overall health and metabolism Lifestyle factors like sun exposure and diet General Guidelines: Mild results : 1015 sessions Moderate improvement : 1530 sessions Significant lightening : 3040 sessions Sessions are typically spaced once or twice a week
What it has not done is progress through a regulated clinical-approval pathway
If 100 mcg produces noticeable improvement, stay at this dose
Bowen, A., Kos, K., Whatmore, J., Richardson, S
Simultaneous use of NSAIDs with corticosteroids, anticoagulants, aspirin, platelet inhibitors, and serotonin re-uptake inhibitors can increase gastrointestinal toxicity up to 15-fold