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[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention
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10.1016/j.colsurfb.2022.112999 103 TfilinM.GobshtisN.FozailoffD.FraifeldV
We noticed, however, that the bottom part of subpocket C in the vicinity of the fragments found in the X-ray structures is formed by the hydrophobic portions of D325, Y479, A481, H538, G483, V469, T471 and is likely to prefer bulky hydrophobic substituents
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