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To date, the most promising clinical trial focuses on the progressive muscle disease mitochondrial myopathy 244
People with this chronic, progressive neurological disorder have high levels of oxidative stress and premature cellular die off in a part of the brain called the substantia nigra
Concurrently, it enhances antioxidant defenses through SOD2 and nuclear factor erythroid 2-related factor 2 (Nrf2) upregulation (43), ameliorating hepatic inflammation in NAFLD models
Many patients report significant changes in hunger levels, fullness cues, and even food preferences
doi: 10.7554/eLife.39340
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