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Lifestyle Modifications : Patients should avoid or minimize factors that accelerate bone loss, including smoking cessation and limiting alcohol consumption to no more than one drink daily for women or two for men

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Given that such data are not entirely homogenous with RCTs in terms of design and control conditions, they are best utilized as exploratory indicators of potential effect ceilings and accessibility to calibrate clinical expectations, rather than as direct points of comparison for placebo-controlled RCTs