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The combined effect is usually clinically minor but worth monitoring in patients with hypertension or heart disease

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N-Acetyl Cysteine (NAC): A glutathione precursor NAC is a precursor to glutathione, meaning it helps the body produce more of this vital antioxidant

Other mouse strains such as C3H or BALB/c would be the next option though some aspects of human pathophysiology may not be replicated in these strains