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Research in people with type 2 diabetes has found that GLP-1 users have a higher chance of gallbladder and bile duct problems compared with those on other diabetes medications
This serious condition causes muscle twitching or rigidity, confusion, seizures, heavy sweating, diarrhea, and irregular heartbeat
Thus, RGDV Pns11-induced tubules potentially mediate viral spread from the testis epithelium into the sperm lumen by overcoming the member barrier of apical plasmalemma, consistent with previous findings that Pns11-induced tubules could facilitate viral spread among insect vector cells 35
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