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The following diagrams shows some of these reasons
Deijen JB, de Boer H, van der Veen EA
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GSH reverses OGD-mediated ferroptosis by activating the SLC7A11/GPX4 axis We investigated the mechanism by which GSH enhances the resistance of ADSCs to ferroptosis
The serum-induced increase in p53 ubiquitination was blocked by a PI3K inhibitor, suggesting that phosphorylated Akt enhances the ubiquitination-promoting function of MDM2, determining reduction of the p53 protein
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