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health insurance claims data for more than 50 million people from 2022-2024 and determined that, after an initial jump in spending related to the start of injectable GLP-1 drugs like Ozempic (NVO) and Wegovy, cost growth for the treatment group trended at half the rate of a control group in the second year

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Most frequently, participants on tirzepatide experienced diarrhea, nausea, constipation and vomiting

These findings suggest that increased DPP-4 activity could indirectly foster bone resorption while hindering bone formation, thereby elevating the risk of osteoporosis