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2,5-7 GLP-1 receptors are present throughout the body, including the skin, central nervous system (eg, hypothalamus, brainstem, amygdala, hippocampus, cerebellum, spinal cord), vagus nerve, gastrointestinal system, pancreas, kidneys, and lungs
Early-stage molecules, novel peptides, and laboratory reagents still fit squarely within the RUO framework
resume treatment if significant regain occurs Accept that some regain is normal and doesn't indicate failure Many individuals require ongoing medication for sustained weight loss maintenance, similar to other chronic disease treatments
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