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For a GFR decrease from 95 to 74 (28 % change), the creatinine increased from 1.0 to 1.5 mg/dL (50 % change)
Engl J Med
This rapid saturation is a stark contrast to standard oral glutathione, which often takes up to six months of high-dose supplementation to achieve similar systemic elevations
Therefore, it is clinically meaningful to assess the level of total erythrocyte GSH as an indicator of GSH status and metabolism
Upon approval and consent by the representatives, verbal and/or written consent was obtained from the parent and/or guardian of the children who participated in the study
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