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When people say peptides, they often mean different things, but in weight care, the most established peptide-based tools are GLP-1 medications and dual agonists like tirzepatide

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We examine the role of receptor binding kinetics and -arrestin-biased signaling in the observed trafficking profiles, identifying a linked set of agonist characteristics optimally suited for insulin secretion, not shared by GLP-1R agonists in the current clinical use

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