higher doses yield diminishing returns
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Previous studies have elucidated that AGE-RAGE pathway can affect bone homeostasis in multiple links, including biomineralization [57], osteogenesis [58], osteoclastic differentiation [59], etc
TXNDR1 expression is however relatively homogenous in HSCs and the myeloid lineage and in different AML subtypes
Annu Rev Biochem 76:295329 Ramos P, Schmitz M, Gama S, Portantiolo A, Durruthy MG, de Souza Votto AP, Cornetet LR, dos Santos MK, Werhli A, Tonel MZ, Fagan SB, Yunes JS, Monserrat JM (2018) Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays