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Size and scope differ, but neither factor determines clinical results
Patients should also have a clear plan for what happens if the medication is stopped, changed, unavailable, not tolerated, or no longer needed
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Rather than conducting a new meta-analysis, the authors synthesize findings from major randomized clinical trials, highlighting outcomes related to glycated hemoglobin (HbA1c), body weight reduction, major adverse cardiovascular events (MACE), and kidney function decline as reported in large cardiovascular outcomes trials (CVOTs), obesity randomized controlled trials, and early-phase clinical development studies
6.5%, PR 1.30 [95% CI 0.81-2.06])
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