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Last updated: January 28, 2026 As GLP-1 medications like Ozempic, Wegovy, and Mounjaro help more patients achieve significant weight loss, many are discovering that reaching their goal weight reveals new concerns: stubborn fat pockets and loose abdominal skin that diet and exercise cannot address
By the time three months have passed, your slimmer shape is readily noticeable
However, follow your surgeon's recommendation on weight loss, especially if you've had a fat transfer
But the thigh is the best option for people who experience significant nausea, prefer clear visibility of the injection, or have limited subcutaneous fat in the abdominal area
In the phase 3 OASIS 4 trial, adults taking a 25 mg daily dose of oral semaglutide lost an average of 13.6% of their body weight, compared with a placebo
