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Reduces inhibition around eating: Alcohol can make it harder to manage eating behaviors, which may lead to increased calorie intake and interfere with weight loss progress

Some individuals report that hunger feels more intense initially, though this likely represents return to baseline rather than true rebound hyperphagia

The most suitable sites for injections are: Abdomen: Avoid the area 2 inches around the navel Front of the thighs: Choose a spot away from the direct midline or any muscular regions Upper arms: Particularly the backs, where there is typically more fatty tissue Avoid injecting into lean or muscular areas, as this can be painful, cause more bleeding than usual, and potentially reduce the drugs effectiveness

Spadaro, A., Scott, K

This is attributed to GLP-1 receptor activity in the hypothalamus and brainstem, which modulates satiety signalling