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P., Cristaldi, E., Colonna, V., Messano, M., Koverech, A., Neri, S., Vacante, M., Cammalleri, L., and Motta, M
Open 4 (3), e211031
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Somatostatin Inhibition Kinetics: Investigating the capacity of the dual ghrelin receptor agonists to down-regulate the inhibitory influence of somatostatin (growth hormone-inhibiting hormone), thereby extending the duration of simulated secretory phases
The clinical implication is that intermittent pulsatile dosing, rather than multiple daily injections, is the strategy most consistent with preserving receptor sensitivity for either compound
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