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Yang N, Garcia MA, Quinton PM
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183 In addition, rational combination regimens, such as HDACis with EGFR-TKIs, DNMTis with platinum agents, or BET inhibitors with antiPD-1/PD-L1 antibodies, have demonstrated synergistic efficacy by simultaneously targeting multiple resistance pathways
The clinical responses, when delivered properly, are meaningful
Most protocols suggest administration first thing in the morning on an empty stomach and again before bed
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