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Hypoxia and inflammation activate p53 via phosphorylation
3 (July 21, 1994): 161-167, 331
It has been studied for decades in skin biology and is widely used as an active ingredient in topical skincare
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Its mechanism of action centers on upregulation of growth factor expression, particularly vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF), which accelerate angiogenesis and tissue granulation 5
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