Summary Vitamin B12 injections can be an effective way of treating a deficiency
In contrast, there is strong support for the hypothesis that ferrous iron in mitochondria is essential for protein nitration by peroxynitrite [75]
Vitamin B12 is reduced to cobalamin regardless of form (cyan-, methyl-, adenosyl-, hydroxo-) then re-assembled as methylcoblamin by MS for use in the cytosol, or adenosylcobalamin by MM for use in the mitochondria
13(2) 85-115 Taglialatela G, Angelucci L, Ramacci M, Werrbach-Perez K, Jackson G, Perez-Polo J (1991) Acetyl-L-carnitine enhances the response of PC12 cells to nerve growth factor
While many people get sufficient amounts through diet or supplementation, some individuals require more direct forms of administrationsuch as injectionsdue to medical conditions or absorption issues