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Key Takeaways Semaglutide is used for treating type 2 diabetes and obesity
It is not appropriate for pregnant individuals and should be avoided in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
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We randomly assigned patients to two groups using an Excel (Microsoft Corp., Redmond, WA, USA)-based allocation system with stratification and 1:1 allocation via permuted-block randomization
Additionally, it enhances insulin secretion in response to meals while suppressing glucagon release, which helps regulate blood sugar levels and may indirectly support weight management
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