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One study in diet-induced obese mice found that an NNMT inhibitor combined with a calorie-restricted diet was associated with shifts in gut bacterial populations, suggesting metabolic intervention can have knock-on effects on gut composition

Fast Facts B12 injections can be more effective than pills in certain patients who have trouble absorbing vitamin B12

However, complete symptom resolution often requires several weeks to months of consistent treatment

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Unfortunately, its also one of the vitamins that people are most likely to be deficient in, especially if they are vegetarian or vegan, are over 50, or have conditions that affect absorption