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In clinical trials, about 74% of people on the 25-milligram oral dose experienced some gastrointestinal symptomsprimarily nausea, vomiting, or diarrhea

Compounded versions of both medications cost significantly less, often $100 to $400 per month depending on the pharmacy and dose

The medication has a half-life of about one week, which allows for weekly dosing, but skipping doses or inconsistent timing can create gaps in coverage where appetite suppression weakens, and blood sugar control falters

Starting low and increasing slowly makes a substantial difference in tolerability

However, the current research is limited with regard to exploring the effects of L-carnitine on brain function