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Systemically administered, fluorescently labelled exendin-4 accesses the LDTg, and administration of exendin-4 into this brain region suppresses food intake without causing aversion [92], unlike in the LC [91]
You can read the full article at Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials
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Abbreviations Agrp: Agoutirelated peptide AUC: Area under the curve BLA: Basolateral amygdala dSTR: Dorsal striatum FRU: Maternal fructose diet GLU: Maternal glucose diet HDL: Highdensity lipoprotein IPGTT: Intraperitoneal glucose tolerance test LDL: Lowdensity lipoprotein Mc4r: Melanocortin4 receptor NAc: Nucleus accumbens PCA: Principal component analysis PL: Prelimbic cortex PND: Postnatal day Pomc: Proopiomelanocortin SD: Control diet/Maternal control diet SPT: Sucrose preference test References Marshall NE, Abrams B, Barbour LA, Catalano P, Christian P, Friedman JE, et al
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