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Mol Metab 2022;66:101633.ArticlePubMedPMC 110
Common pathophysiological mechanisms of metabolic syndrome and NDD include insulin resistance of the brain, neuroinflammation, oxidative stress, dysfunction of the BBB, mitochondrial damage, dysbiosis of the intestinal microbiota and changes in the renin-angiotensin system
Indications for use GLP-1 receptor agonists are used to manage type 2 diabetes and, in some cases, for weight loss in people with obesity or who are overweight with related health conditions
At the moment, taking Rybelsus requires certain adherence conditions, such as taking the pill on an empty stomach, Thiara said
Concomitant oral anti-diabetic drugs (OADs) were allowed for all trials (except in SUSTAIN 1, which was a monotherapy trial)
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