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Antigen-presenting cells, including dendritic cells and macrophages, convey antigens to naive T lymphocytes, triggering their activation and differentiation, CD4 + T helper cells are essential for coordinating immune responses by aiding B cells and activating cytotoxic CD8 + T cells, B lymphocytes mature into plasma cells, which generate antibodies that combat infections and facilitate their eradication [93]

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NAD+ deficiency could indicate muscle loss, oxidative stress, and the start of many life-limiting diseases

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