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The most recent comprehensive synthesis is a July 2025 systematic review in the HSS Journal , the musculoskeletal journal of the Hospital for Special Surgery in New York, led by Nikhil Vasireddi at Case Western Reserve University School of Medicine
Johns Wort: Fact sheet
Common side effects include redness, swelling or pain at the injection site, mild diarrhoea, itching, and a feeling of swelling all over the body
the WHO 2021 no-safe-level guideline
These symptoms often build up slowly, making them easy to overlook
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