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While effective for short-term weight loss, it comes with significant drawbacks: Only FDA-approved for short-term use (up to 12 weeks) Can cause increased heart rate, anxiety, and insomnia Has addictive potential as a Schedule IV controlled substance Weight regain is common after stopping the medication Topamax (Topiramate) Topiramate is an anticonvulsant that has been prescribed off-label for weight loss due to its ability to suppress appetite
These are often better suited to mild to moderate laxity, and can be combined with other treatments when appropriate
Given the aggressive nature of MPNST and its high rate of local recurrence and metastasis, early diagnosis and coordinated care at specialized sarcoma centers are essential (Widemann & Italiano, 2018)
We also know that when people stop taking the medication without adequate lifestyle support, the weight comes back
Intramuscular injection typically causes sharper pain during injection, more bleeding afterward, and sometimes a dull ache that persists for hours
