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Ginsenoside F2 restrains hepatic steatosis and inflammation by altering the binding affinity of liver X receptor coregulators

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Our results show that glutathione efflux from hepatocytes results in high local concentrations of both glutathione and cysteine in liver sinusoids, which transforms the nanoparticle surface chemistry, reduces its affinity to serum protein and significantly alters its blood retention, targeting and clearance

Further studies suggested that GLP-1 stimulates both synthesis and secretion of insulin via multiple cAMP-dependent pathways

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