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The typical sites are the upper arm, thigh, or gluteal muscles for IM injections, and a suitable vein for IV injections
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Independent testing has found frequent mislabeling, underdosing, or contamination
Spironolactone is contraindicated in patients with hyperkalemia (high potassium), severe kidney disease, Addisons disease, or those taking certain medications (potassium supplements, ACE inhibitors, ARBs in high doses)
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