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As OxS plays an important role in PSC activation and pancreatic fibrosis, we hypothesized that high glucose could stimulate pancreatic cells to produce excess ROS and activate PSCs, that induce pancreatic fibrosis and ultimately lead to -cell failure

reacts reversibly with methylmaleic anhydride (also called citraconic anhydride) in a nucleophilic substitution reaction

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Compound Tirzepatide and Customization Due to demand, compound tirzepatide is increasingly available through specialized pharmacies for research purposes