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Journal Biological Macromolecules 246, 125673

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(4) Blood Pressure (3) In blood pressure studies, compared with l-arginine, pentadecapeptide BPC 157 (without effect on basal normal values) had both a mimicking effect (impaired l-NAME-blood pressure increase, when applied prophylactically and decreased already raised l-NAME values, given at the time of the maximal l-NAME-blood pressure increase (i.e., 10 min after l-NAME)) and preventive activity (l-arginine-induced moderate blood pressure decrease was prevented by BPC 157 pretreatment)

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After 6 weeks, the collagen-treated subjects showed significant improvements in skin wrinkle parameters and skin moisturization, but the supplement did not significantly modify skin firmness or elasticity