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In ALS models, SOD1 mutations do not markedly alter astrocytic baseline states but lower the threshold for reactivity, which sensitizes astrocytes to oxidative, glutamatergic and inflammatory stress and drives exaggerated reactive responses to otherwise moderate insults 80

Glucagon-like Peptide-1 Receptor Agonists Associated Gastrointestinal Adverse Events: a Cross-Sectional Analysis of the National Institutes of Health All of Us Cohort

Theres a difference in the two curves, but it was there from the beginning

The rationale underlying the analysis implies that an individual experiencing efficacy and tolerability of a treatment is unlikely to change to another treatment

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