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If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia

Protocols account for the hormonal and metabolic differences between genders

Signs of Semaglutide Overdose According to the Missouri Poison Control Center, the signs of semaglutide overdose include: Feeling lightheaded or dizzy Feeling shaky or jittery Sweating, chills, and clamminess Irritability or impatience Headache Weakness Fatigue Nausea and or vomiting Confusion Passing out Seizures If you think you have overdosed on semaglutide, call you local poison control center or the national hotline: 1-800-222-1222.

Gradual dose titration, dietary modifications, and adequate hydration help minimise gastrointestinal adverse effects and improve treatment tolerance

Even among those who are prescribed treatment, only about half take the medication beyond one year