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Results The model detected 112,274 T2D patients who did not receive insulin therapy and started GLP1-receptor agonists (28,081 individuals) or SGLT2 inhibitors (84,193 individuals) in the United Kingdom (UK) from January 2013 to October 2020

Resolves quickly with proper fluid intake but requires ongoing vigilance Serious But Less Common Side Effects The MHRA highlights several serious but less common risks that patients should know about 1 : Gallbladder problems: Including gallstones Pancreatitis: Inflammation of the pancreas, which can require hospitalization Allergic reactions: Can include swelling, rash, and trouble breathing Low blood sugar: Can happen even in non-diabetic patients using GLP-1s for weight loss Hair loss: Some patients report temporary thinning of hair Warnings About Misuse Healthcare professionals are concerned about people using GLP-1 medications inappropriately just for cosmetic weight loss

Medication Impact / Treatment Pharmacologic management is relevant in the peri-operative and chronic post-amputation setting

Over time, your body should adjust to your new calorie intake

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