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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

This makes it suitable for individuals who do not need appetite control or cannot tolerate GLP-1 agonist side effects

Initial Loading Dose: At first, people get 1000 mcg every week for 4-8 weeks