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Acetyl-L-Carnitine (ALC) Acetyl-L-Carnitine vs L-Carnitine Acetyl-L-carnitine (ALCAR) demonstrates superior blood-brain barrier penetration and enhanced neuroprotective effects compared to L-carnitine (LCAR), making it the preferred choice for neurological applications, while both compounds show similar efficacy for peripheral and metabolic indications
Hann, S
Cancer Res 63 : 627635 Sciacca L, Mineo R, Pandini G, Murabito A, Vigneri R, Belfiore A (2002) In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A
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Our findings are consistent with previous studies showing additional metabolic-cardiovascular-renal benefits of combined GLP-1RA and SGLT2i use in patients with T2D 26 , and suggest a promising role for adding GLP-1RA to SGLT2i therapy in patients with MASLD
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