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Mitochondrial dysfunction and oxidative stress: a vicious cycle In ME/CFS, elevated ROS and RNS levels are associated with mitochondrial dysfunction by damaging mtDNA and membranes, disrupting the ETC, and triggering mitophagy

Semaglutide is contraindicated in patients with personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2

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This prevents needle-stick injuries and ensures safe disposal