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Given the pronounced effect of tau elimination observed in in vitro and in vivo studies, selecting patients who test positive for tau biomarkers (CSF, blood, or positron emission tomography) could enhance the likelihood of achieving significant disease modification

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Obese patients (BMI 30-35) often need 400-500mcg achieving similar IGF-1 increases as normal-weight patients at lower doses

Topical, Injectable, or Oral: Which Delivery Method Actually Works The delivery method matters as much as the peptide itself

Any decision to stop belongs with the prescribing provider