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In vitro studies suggest GHK-Cu may stimulate collagen synthesis and fibroblast activity
A: Alternatives to estradiol patches include FDA-approved transdermal gels and sprays, oral estradiol (with a different clot-risk profile), vaginal estrogen preparations for genitourinary symptoms, and compounded transdermal estradiol creams from PCAB-accredited pharmacies
Initial doses are typically conservative to assess tolerability and tissue response before titration upward
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