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How the medications work GLP-1 receptor agonists engage the GLP-1 receptor across the pancreas, hypothalamus, and gastrointestinal tract, slowing gastric emptying, blunting post-meal glucose excursions, reducing appetite, and strengthening satiety signaling
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This has resulted in increased reliance by clinicians on the intensity of pain reported by patients when making decisions regarding opioid prescriptions
Third, semaglutide might alter dopamine pathways, helping to manage the reward-seeking behaviors central to OCD
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