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The EXSCEL trial with exenatide showed similar glycemic and weight benefits, accompanied by trends toward better microvascular outcomes [30]
Both TB-500 and BPC-157 are explicitly listed under WADA Code S0 (non-approved substances) and have been since 2011 and 2019 respectively, which means any athlete in WADA-tested competition who tests positive faces a sanction regardless of intent or formulation
GLP-1 receptors are expressed throughout the central nervous system, including in the hypothalamus, which governs hunger and energy balance, and in the mesolimbic dopamine pathway the brain's reward circuit
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Bupropion functions as a noradrenaline-dopamine reuptake inhibitor (NDRI), modulating neurotransmitter activity in the central nervous system
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