It is generally recommended to stop GLP-1 receptor agonist medications such as Ozempic, Mounjaro or Wegovy before conception and allowing for a washout period of approximately 23 months
GLP-1 analogues, including semaglutide, have been instrumental in managing type 2 diabetes
This, in turn, results in higher potency
[10] reported that metformin acutely and selectively increased plasma levels of GLP-1 in mice, even in the absence of concomitant oral glucose administration, while it did not increase plasma levels of the other incretin hormone, glucose-dependent insulinotropic polypeptide (GIP), or, curiously, peptide YY, a gastrointestinal hormone co-localised with GLP-1 in L cells
Some users may experience dyspepsia, gastritis, gastroesophageal reflux disease, or gallstones