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Interestingly, the other mitochondrial enzyme (GLS2) involved in glutamine degradation impairs tumorigenesis, being frequently downregulated in tumors

doi: 10.1016/j.jaut.2016.02.001 66 TomitaT

This discovery eventually led to the use of certain GLP-1 medications as part of medically supervised weight management programmes and obesity treatment

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Semaglutide remains the right call if you have established cardiovascular disease (SELECT data), chronic kidney disease with T2D, or MASH with an FDA indication today